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Smiles for Rach

Kathy
on 17 Jan 2018

Kathy asks

Here is a medical study (pubmed) on use of interferon which was new treatment 8 years ago when my friend was put on it. If you aren't on this treatment or don't know about it please ask for this article released 2008.

"Immunol Lett. 2008 Jun 30;118(2):110-5. doi: 10.1016/j.imlet.2008.03.016. Epub 2008 May 5.

Interferons and scleroderma-a new clue to understanding the pathogenesis of scleroderma?

Coelho LF1, de Oliveira JG, Kroon EG.

Author information

Abstract

Scleroderma or systemic sclerosis (SSc) is a complex disease characterized by vasculopathy and deregulated immune and fibroblast activation. The resulting excessive production of collagens and other extracellular matrix proteins by fibroblasts as well as the inflammatory response leads to the development of scleroderma. Recently, some emerging data have been showing a possible link between the type I and II interferons (IFNs) and SSc pathogenesis. IFNs are well-known immunomodulators and inhibitors of collagen production. However, IFN therapy also has been implicated in the development or exacerbation of several autoimmune diseases, including SSc. Some studies also showed an increase mRNA and protein levels of IFNs and several interferon stimulated genes in cells and tissues from SSc patients. In this review we discuss about a possible role for IFNs in SSc development and pathogenesis." Kathy

Rebecca

Hi Kathy, thank you for the information. I have passed this on to Ange for her to look into. I'm sure it will be very helpful.

Kind regards,

Rebecca

Rebecca Gudsell
Kathy
on 17 Jan 2018

Kathy asks

Hi Rebecca, I was sorry to hear of your condition. I have a friend with scleroderma and its in the organs. She has treated it for 8 years very successfully with interferon and a plant based vegan diet. I would encourage you to ask your doctor for this option and a change of diet can't hurt! If your Doctor hasn't heard of this option I would suggest you do some research or get another opinion. It works! Meanwhile take care and good luck! Kathy

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