How are Gut bacteria involved in causing Bowel Cancer?

$30 of $29,296 goal
Given by 3 generous donors in around 8 months

We aim to identify bacterial communities that are involved in the development of Bowel Cancer


What we aim to do

We plan to identify bacterial communities that are specific to certain types of polyps and, importantly, identify the functions of these bacteria that may play a role in initiating Bowel Cancer.

Then, we will test the mechanisms by which these bacteria interact with cells in the colon to cause cancerous changes.

How we plan to do it

We will use polyps that have been collected by the Cancer Tissue Bank and extract DNA and RNA from them. Using cutting-edge DNA and RNA sequencing technology, we will identify differences in bacterial communities and functions between different types of polyps, and compare them to colon tumour tissue and healthy bowel tissue. This will allow us to identify bacterial functions and components that are only present in pre-cancerous lesions.

We will then test how these bacterial components may initiate cancer in colon cells in the laboratory and investigating changes at the molecular levels in the cells.

How your donation will help

Dr Purcell who is undertaking this research is looking for funds to pay for a Research Assistant’s salary to assist with the completion of this research.

We will be having events for World Microbiome day which you can contribute to. You may even want to run your own Gut Biome event and set up your own page.

About us

The Gut Foundation is the New Zealand charity working to beat Gut Disease but we can't do it on our own. Join us - become a "Gutsy Hero" Change our dreadful statistics for Gut disease in NZ

Use of funds

The only cost we have to cover is a salary cost of $56,296. We have already raised $27,000 so we need another $29,296.

Read more

Latest update

Update image

Your MicroBiome and Bowel Cancer  28 June 2021

Don't just moan about Bowel cancer statistics support research and save lives in the future

Share this update

View and comment

Read more

Latest donations

Shirley on 26 Jan 2021
John on 26 Jan 2021
Private Donor
Private Donor on 26 Jan 2021

Who's involved?

The Bowel and Liver Trust Canterbury's avatar
Created by, and paying to a verified bank account of, The Bowel and Liver Trust Canterbury (Charity)
Registered Charity
A Registered Charity has legal recognition under the Charities Act 2005.
Tax credit
Donations of over $5 are eligible for a New Zealand charitable giving tax credit.
Page Moderated
The page has been checked by our team to make sure it complies with our terms and conditions.

Want to get in touch with The Bowel and Liver Trust Canterbury?

Ask a question here

Want to display a QR code that links to this page?

Grab a QR Code

Any concerns?

Report this page
This page was created on 15 Jan 2021 and closed on 31 Aug 2021.