How are Gut bacteria involved in causing Bowel Cancer?

$30 of $29,296 goal
Given by 3 generous donors in around 8 months

We aim to identify bacterial communities that are involved in the development of Bowel Cancer

Nationwide

What we aim to do

We plan to identify bacterial communities that are specific to certain types of polyps and, importantly, identify the functions of these bacteria that may play a role in initiating Bowel Cancer.

Then, we will test the mechanisms by which these bacteria interact with cells in the colon to cause cancerous changes.

How we plan to do it

We will use polyps that have been collected by the Cancer Tissue Bank and extract DNA and RNA from them. Using cutting-edge DNA and RNA sequencing technology, we will identify differences in bacterial communities and functions between different types of polyps, and compare them to colon tumour tissue and healthy bowel tissue. This will allow us to identify bacterial functions and components that are only present in pre-cancerous lesions.

We will then test how these bacterial components may initiate cancer in colon cells in the laboratory and investigating changes at the molecular levels in the cells.

How your donation will help

Dr Purcell who is undertaking this research is looking for funds to pay for a Research Assistant’s salary to assist with the completion of this research.

We will be having events for World Microbiome day which you can contribute to. You may even want to run your own Gut Biome event and set up your own page.

About us

The Gut Foundation is the New Zealand charity working to beat Gut Disease but we can't do it on our own. Join us - become a "Gutsy Hero" Change our dreadful statistics for Gut disease in NZ

Use of funds

The only cost we have to cover is a salary cost of $56,296. We have already raised $27,000 so we need another $29,296.

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Latest update

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Your MicroBiome and Bowel Cancer  28 June 2021

Don't just moan about Bowel cancer statistics support research and save lives in the future

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Latest donations

Shirley
Shirley on 26 Jan 2021
$10
John
John on 26 Jan 2021
$10
Private Donor
Private Donor on 26 Jan 2021
$10

Who's involved?

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This page was created on 15 Jan 2021 and closed on 31 Aug 2021.